RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-185
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
qRT-PCR; Dual-luciferase reporter assay; etc.
Target
COL5A1
Pathway
NA
PubMed ID
Title
Regulation of Collagen V Expression and Epithelial-Mesenchymal Transition by miR-185 and miR-186 during Idiopathic Pulmonary Fibrosis
Year
2016
Function
"The expression levels of miR-185 and miR-186 were decreased in the lungs of idiopathic pulmonary fibrosis patients.Attenuated expression of miR-185 and miR-186 may be responsible for collagen V overexpression during idiopathic pulmonary fibrosis, and these miRNAs may serve as pathogenesis-related biomarkers and treatment targets."